In recent years, the global pharmaceutical industry has begun to conduct clinical trials outside of the United States, Japan, and Europe. This globalization of research and development raises essential concerns about the cultural aspects of clinical research, the communication of global scientific knowledge, the changing structure of the industry, the new spatial division of labor occupied by patients, doctors, and pharmaceutical company employees around the globe, the role of the nation-state in this new globalization process, international bioethics, and the unequal stratification of benefits and harm that global research entails. This project examines the cultural, political, economic, and ethical implications of the expansion of clinical research into the developing world through a “multi-sided ethnography” with research sites in Mexico and the US pharmaceutical industry sponsors, emphasizing transnational processes, connections, and the stratification of power.